Discovery Guides Areas


Anthrax (Bacillus anthracis)
(Released November 2001)

  by Roberta A. Gardner  


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  1. The probability of severe disease in zoonotic and commensal infections
    Proceedings of the Royal Society of London, Series B: Biological Sciences [Proc. R. Soc. Lond., Ser. B: Biol. Sci.], vol. 268, no. 1462, pp. 53-60, 7 Jan 2001

  2. Role of toxin functional domains in anthrax pathogenesis
    Infection and Immunity [Infect. Immun.], vol. 68, no. 4, pp. 1781-1786, Apr 2000

  3. PCR Amplification on a Microarray of Gel-Immobilized Oligonucleotides: Detection of Bacterial Toxin- and Drug-Resistant Genes and Their Mutations
    Biotechniques, vol. 29, no. 4, pp. 844-857, Oct 2000

  4. Trp 346 and Leu 352 Residues in Protective Antigen Are Required for the Expression of Anthrax Lethal Toxin Activity
    Biochemical and Biophysical Research Communications [Biochem. Biophys. Res. Commun.], vol. 281, no. 1, pp. 186-192, 16 Feb 2001

  5. Point Mutations in Anthrax Protective Antigen That Block Translocation
    Journal of Biological Chemistry [J. Biol. Chem.], vol. 276, no. 11, pp. 8371-8376, 16 Mar 2001

  6. Dehydroepiandrosterone and melatonin prevent Bacillus anthracis lethal toxin-induced TNF production in macrophages
    Cell Biology and Toxicology [Cell Biol. Toxicol.], vol. 16, no. 3, pp. 165-174, 2000

  7. Bacterial skin infections in a tropical environment
    Current Opinion in Infectious Diseases [Curr. Opin. Infect. Dis.], vol. 14, no. 2, pp. 123-126, Apr 2001

  8. A Dominant Negative Mutant of Bacillus anthracis Protective Antigen Inhibits Anthrax Toxin Action in Vivo
    Journal of Biological Chemistry [J. Biol. Chem.], vol. 276, no. 25, pp. 22090-22094, 22 Jun 2001

  9. Intracellular calcium antagonist protects cultured peritoneal macrophages against anthrax lethal toxin-induced cytotoxicity
    Cell Biology and Toxicology [Cell Biol. Toxicol.], vol. 16, no. 2, pp. 137-144, 2000

  10. Involvement of Domain 3 in Oligomerization by the Protective Antigen Moiety of Anthrax Toxin
    Journal of Bacteriology [J. Bacteriol.], vol. 183, no. 6, pp. 2111-2116, Mar 2001

  11. Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin
    Infection and Immunity [Infect. Immun.], vol. 69, no. 2, pp. 1175-1177, Feb 2001

  12. Dominant-negative mutants of a toxin subunit: An approach to therapy of anthrax
    Science (Washington) [Science (Wash.)], vol. 292, no. 5517, pp. 695-697, 27 Apr 2001

  13. Role of residues constituting the 2 beta 1 strand of domain II in the biological activity of anthrax protective antigen
    FEMS Microbiology Letters [FEMS Microbiol. Lett.], vol. 199, no. 1, pp. 27-31, 15 May 2001